LOCKLAB BLOG

The Locklab Pill

Locklab medication overview

Locklab is a 3-in-1 compounded medication containing Oral Minoxidil, Oral Finasteride, and Oral Biotin. This overview reviews the risks and benefits of using Locklab to treat male pattern hair loss (androgenic alopecia).

How does Locklab work?

Minoxidil works by boosting blood flow, oxygen, and nutrients to hair follicles, which puts hair into the growth phase (anagen phase) indefinitely where hair becomes thicker and fuller.

Finasteride prevents the loss and conversion of testosterone to its active metabolite, DHT. By blocking this conversion, finasteride decreases the level of DHT and the resulting hair loss it causes.

Biotin is a B vitamin essential for metabolism that is often used to support healthy hair, skin, and nails.

How should I take Locklab?

  • Locklab should be taken by mouth once daily, with or without food.
  • If you miss a day, don’t double up, just skip that dose and take it as usual the next day. There are no additional benefits from taking Locklab more than once a day.
  • Many patients find success setting a daily reminder on their phone to take Locklab in the morning.
  • If you experience lightheadedness as a side effect, take it at night, but try to take your pill at the same time every day to maximize effectiveness.

What should I expect during treatment?

  • You may experience increased hair shedding in the first 2-8 weeks as beneficial hair cycling is triggered. This is normal and means that the medication is working.
  • The full benefits of finasteride and minoxidil are seen within 6-12 months, but results may be seen as early as 2-3 months.
  • Successful treatment is defined by both hair growth and stopping hair loss from getting worse, since male pattern baldness naturally gets worse over time.
  • You will continue to shed hairs at a normal healthy rate (50-100 hairs per day) while using Locklab. Even if you stop hair loss, shedding hair is part of your body’s natural hair growth cycle. Each hair sheds once it grows to a certain length, comes to the end of its natural cycle, and falls out. Afterwards, a new hair starts growing in its place.

What happens if I stop taking Locklab?

  • Like all hair loss treatments that actually work, you need to keep taking Locklab consistently to maintain the results from it.
  • If you stop taking Locklab, you'll lose your progress and your hair will return to what it would have looked like if you never started treatment.

Minoxidil

About

Oral minoxidil is a prescription medication proven in decades of clinical trials to stimulate hair growth. It has been found that that the higher the dose, the greater the clinical effect; however, it is important not to take more than your healthcare provider has prescribed to you. Ask your healthcare provider or pharmacist if you have questions.

What should I tell my healthcare provider before taking oral minoxidil?

They need to know if you have any of these conditions:

  • Low blood pressure (hypotension)
  • High blood pressure (hypertension)
  • Heart disease
  • Kidney disease
  • Pheochromocytoma
  • Currently taking a medication called guanethidine
  • Sudden or patchy hair loss
  • Unknown reason for hair loss
  • An unusual or allergic reaction to minoxidil or any components of the medication
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medicine?

Minoxidil is contraindicated in patients who are currently taking guanethidine.

This list may not describe all possible interactions. Give your healthcare provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also, tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Potential side effects

Side effects that you should immediately report to your doctor or health care professional:

  • Lightheadedness, dizziness, racing or irregular heartbeat
  • New or worsening chest, arm, or shoulder pain
  • Shortness of breath
  • Rapid weight gain, or swelling in the hands, legs, or feet
  • There is a rare chance of pericardial effusion (fluid around the heart)

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • Nausea and/or vomiting
  • Unusual or increased hair growth, on the face and/or body

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. 

Finasteride

About

Finasteride is used to treat male pattern baldness in men only. This medicine is not for use by women.

Who should not take this medicine?

This medicine is for men only and should not be taken by women. Finasteride can affect hormone levels so it is very important that women who are pregnant or could become pregnant don't handle it, as it can lead to complications with pregnancy.

If you have the following conditions, do not take this medication before informing your doctor:

  • Liver disease or problems
  • Kidney problems
  • Prostate cancer
  • You are pregnant or trying to get pregnant
  • You are breastfeeding

Do not take this medicine if you are allergic to finasteride (including Proscar and Propecia®).

Potential side effects

Like all prescription products, finasteride may cause side effects. Contact your doctor or a health care professional immediately if you experience any of the following:

  • Signs of serious allergic reactions like skin rash, itching, swelling of the face, lips, or tongue, extreme dizziness, difficulty breathing
  • Swelling or tenderness in the breasts or pain or fluids leaking from the nipple
  • Pain in the testicles
  • Inability to urinate
  • Depression

Though rare, in clinical trials, 3.8% of male patients noticed some form of sexual side effects (versus 2.1% of patients taking the placebo). It’s important to note that only 1.2% of men taking finasteride actually stopped treatment (versus 0.9% of the placebo group) since the majority of side effects resolve themselves. So if the same percentage of men in the finasteride group also incorrectly attributed side effects to finasteride, then the total proportion of men who stopped treatment would be only 0.3%. It has been reported in general use with finasteride tablets that symptoms continue after stopping treatment.

These are not all the possible side effects of finasteride. For more information, ask your healthcare provider or pharmacist. Contact your doctor if you have additional questions about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Biotin

About

Biotin is a B vitamin essential for metabolism that is often used to support healthy hair, skin, and nails.

Potential side effects

We recommend that you do not take additional biotin, since high doses of biotin (5 mg or higher) may interfere with certain lab tests, including specific tests to aid in heart attack diagnosis. Biotin is a vitamin naturally found in food and as such does not generally interact with other medications. However, it's advisable to have a conversation with your healthcare provider before introducing any new supplements. Seeking guidance from a medical professional ensures a thoughtful approach to incorporating dietary enhancements into your daily routine, prioritizing your health and well-being.

Other important information

What should I watch for while using Locklab?

Locklab must be used on a regular basis for your hair to regrow. It typically takes 4 months to notice any improvement and may take up to 12 months of regular use before you reach peak regrowth, although many men reach peak regrowth in 6 months. It is important to continue to use this product to maintain regrowth of hair. Once you stop using it, the regrown hair will usually fall out within 1-6 months. 

What if I miss a dose?

If you miss a dose, don’t double up, just skip that dose and take it as usual the next day. There are no additional benefits from taking Locklab more than once a day.

Blood donations

Do not donate blood while you are taking this medicine. Ask your doctor or health care professional when it is safe to donate blood after you stop taking this medicine.

PSA tests

This medicine can interfere with PSA laboratory tests for prostate cancer. If you are scheduled to have a lab test for prostate cancer, tell your doctor or healthcare professional that you are taking a pill that contains finasteride.

Inform your healthcare providers

Telemedicine does not replace your primary care physician. It is important to keep your primary care and other healthcare providers, and your pharmacists informed of all medications you are taking, including Locklab, as they can interact with other medicines you may be taking.

This page is a summary and may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Follow Up Plan

Your prescription expires after one year. When you run out of refills, you will need to return for a follow-up visit with a Locklab provider to make sure this medication is still appropriate for you.

Use & storage

Store your Locklab tablets at room temperature (between 68 and 77 degrees F) in the packaging provided by the pharmacy until you need it. Keep out of reach of children and pets.

Medication disposal

If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.

If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can visit FDA- Disposal of Unused Medicines for more information or follow these simple steps to dispose of most medicines in your trash at home:

  • Mix medicines (liquid or pills; do not crush tablets or capsules) with an unappealing substance such as dirt, cat litter, or used coffee grounds;
  • Place the mixture in a container such as a sealed plastic bag;
  • Throw away the container in your trash at home; and
  • Delete all personal information on the prescription label of empty medicine bottles or medicine packaging, then trash or recycle the empty bottle or packaging.

Accurate information

Your provider evaluated the specific health information you provided and made recommendations based on it. If you incorrectly or forgot to provide any information, your provider may misdiagnose or fail to diagnose conditions you may have — which could affect their treatment recommendation. If you need to clarify or update any information about your health, please message a provider through your Locklab "Messages" portal.

Treatment failure

This treatment is not 100% effective. It may not work or may partially resolve the condition you are seeking treatment for. If you do not see any signs of improvement or if you are experiencing new or worsening symptoms, message a provider through your Locklab "Messages" portal anytime or contact your regular healthcare provider. If it is an emergency, call 911 or seek immediate help in-person.

Misdiagnosis or delayed diagnosis

There is also a risk that your provider will misdiagnose or fail to diagnose conditions that you may have, which could affect the treatment recommendation. The healthcare providers providing treatment through the Locklab platform use evidence-based guidelines as well as clinical decision-making to minimize these risks.

Accepting or declining the recommendation

Your provider is recommending this treatment for you because the potential benefits outweigh the risks in their estimation. You’re encouraged to evaluate this information, including any input from your in-person healthcare team and any relevant sources to decide if this treatment plan is right for you. You are free to decline recommendations you received from the provider through the Locklab platform.

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